Molecular Formula | C6H5Cl2N |
Molar Mass | 162.02 |
Density | 1.319 |
Melting Point | 42-45℃ |
Boling Point | 187℃ |
Flash Point | 111℃ |
Vapor Presure | 0.891mmHg at 25°C |
pKa | -0.23±0.10(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 1.547 |
Hazard Symbols | T - Toxic |
Risk Codes | R25 - Toxic if swallowed R36 - Irritating to the eyes |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
UN IDs | UN 2811 6.1 / PGIII |
WGK Germany | 3 |
Hazard Class | IRRITANT |
production method | 11g(0.1mol) of dichloroacetonitrile and 14g(0.2mol) of methacrolein are added to 50ml of propiononitrile solvent, 200mg of cuprous chloride and 200mg of tri-n-butyl phosphorus are used as catalysts, placed in a Karnol tube, heated at 130 ℃ for 6h, and cooled to room temperature, the solvent and unreacted raw materials were removed in vacuum, and distilled under reduced pressure at 100-120 ℃/5mmHg to obtain light yellow liquid and slowly crystallize. 2, 3-dichloro-5-methylpyridine 108g was obtained by washing and drying with n-hexane with a yield of 40% mp. 42~45 ℃. |